Nearly 40 years ago, a respected doctor wrote a letter to the New England Journal of Medicine with some very good news: Out of nearly 40,000 patients given powerful pain drugs in a Boston hospital, only four addictions were documented.
Doctors had been wary of opioids, fearing patients would get hooked. Reassured by the letter, which called this “rare” in those with no history of addiction, they pulled out their prescription pads and spread the good news in their own published reports.