The E. coli found infecting a Pennsylvania woman that is resistant to colistin — the antibiotic of last resort — signals that a superbug is inevitable. Circulating among the bacteria in humans are all the antibiotic-resistance genes necessary to create a superbug; they just need to come together in one bacterium. This nightmare scenario highlights two urgent needs: to slow the development of resistant bugs and to spur development of new antibiotics.
Why are we confronting a superbug?
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